CD59

(redirected from H19)

CD59

a glycosylphosphatidylinositol-anchored membrane protein present on many hemopoietic cells, vascular endothelium, epithelial cells, and placenta that inhibits membrane complement attack and may be involved in T-cell signal transduction; absent or defective in paroxysmal nocturnal hemoglobinuria.

CD59

A 65-kD membrane, glycosyl-phosphatidylinositol-anchored complement-neutralising protein encoded by CD59 on chromosome 11p13, which inhibits the complement membrane attack complex, binding to C8 and C9 during assembly of the complex.

Normal expression
Most leukocytes and red cells.

Abnormal expression
May be absent in some forms of paroxysmal nocturnal haemoglobinuria.
References in periodicals archive ?
Its BC-819 clinical stage product candidate is a double stranded DNA plasmid construct that incorporates the gene for diphtheria toxin (DTA) under the regulation of the promoter sequence for H19 gene.
Creation of a material-bed in the region of Ostportals at the railway underpass H19.
In this study, we have examined the allelic counts of 2 RNA transcripts, namely pregnancy-associated plasma protein A, pappalysin 1 (PAPPA) (5), a pregnancy-specific gene, and H19, imprinted maternally expressed transcript (non-protein coding) (H19), an imprinted maternally expressed gene (27, 28).
The objective of this study was to evaluate the effects of different spacing's between or within rows on the agronomic characteristics of three genotypes of Brassica napus new lines (crossed two varieties of H19, goliath), Zarfam and were Pahnab-e-joybar (Local varieties).
We investigated the methylation patterns in DMRs of paternally imprinted gene H19, maternally imprinted genes Peg3 (paternally expressed 3), Snrpn (small nuclear ribonucleoprotein N), Igf2r (insulin-like growth factor 2 receptor), and Pegl in oocytes of control and obese animals and their offspring.
violaceum mutants H19, H20 and H21 expressed moreviolaceum than WT, and were considered hyper producers.
The sprouts used to obtain the mini-cuttings originated from Eucalyptus benthamii x Eucalyptus dunnii mini-stumps (clones H12, H19 and H20) (Figure 1A), grown in a semi-hydroponic system of the 'canaletao' (gutters) type, containing medium sand.
siRNA for H19 Genes Destruction in Cancerous Cells II-54
Association of H19 promoter methylation with the expression of H19 and IGF-II genes in adrenocortical tumors.
Of these genes, only 10 genes have been reported to show imprinting in sheep (GTL2, DLK1, DAT, PEG11, antiPEG11, MEG8, MEST, IGF2, H19 and IGF2r; Killian et al.
Place the cursor in the following cells and hit the Delete key for each: H19, H20, H24, H26 and H27.
That in itself is not satisfactory, but by having a system such as we have with instruction H19 and the review monitoring system, we are doing our best to iron out those sort of problems and bring matters to justice.