H1 receptor


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H1 receptor

a type of histamine receptor on vascular smooth muscle cells through which histamine mediates vasodilation. See also histamine blocking agent.
References in periodicals archive ?
H1 receptor activates phospholipase C and causes smooth muscle contraction especially in intestine.
Diphenhydramine is an inverse agonist of the histamine H1 receptor.
Histamine can also affect other receptors of the cell surface than the H1 receptor, explains Professor Ilkka Harvima of the University of Eastern Finland.
H1 receptor activation also causes smooth muscle contraction in the airways, leading to bronchospasm, and in the GI tract causing nausea, vomiting, bloating abdominal cramps and diarrhoea.
Madam, cetirizine hydrochloride, an antihistamine, is the active constituent of Zyrtec(r) that functions as competitive peripheral H1 receptor inhibitor.
First-generation H1 receptor antagonists achieve receptor blockage in a dose-dependent fashion.
Other new therapeutic options and targets include neurosteroids, selective H1 receptor antagonists, H3 receptor agonists, and substance P.
Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis.
But when pyrilamine blocked the H1 receptor, blood flow to the skin was dramatically reduced.
LAS VEGAS -- Nonsedating H1 receptor antagonists should be frontline therapy in treating chronic idiopathic urticaria, Dr.