FABP3

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FABP3

A gene on chromosome 1p33-p32 that encodes a fatty acid-binding protein thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP3 plays a role in arresting growth of mammary epithelial cells and is a candidate tumour suppressor gene for breast cancer.
References in periodicals archive ?
H-FABP ELISAs (Hycult Biotech; Uden, the Netherlands) were used to detect the concentration of H-FABP in all samples.
Using a high-sensitivity cardiac troponin assay in combination with H-FABP may help further.
1 In this review, in light of the literature, we aimed to evaluate whether H-FABP might be a useful marker in the management of diseases seen frequently in the ED.
Since little work has been done on A-FABP and H-FABP gene expression in chickens, the objective of this research was to detect the relative expression of A-FABP and H-FABP genes in different tissues of chickens using FQ-RT-PCR, and further analyze the correlation between transcription level of A-FABP and H-FABP genes and IMF content.
2] Nonstandard abbreviations: AMI, acute myocardial infarction; cTnT, cardiac troponin T; Flt-1, fms-like tyrosine kinase; PlGF, placental growth factor; sFlt-1, soluble Flt-1; hs-cTnT, high-sensitivity cTnT (assay); NT-proBNP, N-terminal pro-B-type natriuretic peptide; H-FABP, heart-type fatty acid-binding protein.
A pair of primers designed by Alfonso and Arena (2004) was used to genotype the MspI H-FABP.
H-FABP is a 15-kDa cytosolic protein found in heart, muscle, and lactating mammary gland.
H-FABP was first shown to be released from injured myocardium in 1988, after which several studies investigated its application as a biochemical marker of myocardial injury.
Also, subjects with a high BNP level had higher levels of systolic BP, H-FABP, and the AST/ALT ratio and lower levels of ALT and eGFR than those with low BNP.
Recently qualitative rapid immunochemical point-ofcare-tests (POCT) are reliably used to detect H-FABP in capillary blood samples in rapid determination of myocardial damage.
The H-FABP is located on chicken chromosome 23 and is expressed in several tissues; the cellular function of the H-FABP gene has yet to be elucidated in detail (Tyra et al.