ATP6V0A4

(redirected from H(+)-transporting two-sector ATPase, noncatalytic accessory protein 1B)

ATP6V0A4

A gene on chromosome 7q34 that encodes a subunit of H+-ATPase (also known as V-ATPase, vacuolar ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles, which is required for an array of molecular processes, including protein sorting, zymogen activation, receptor-mediated endocytosis and synaptic vesicle proton gradient generation.