ATP6V1F

(redirected from H(+)-transporting two-sector ATPase, 14-kD subunit)

ATP6V1F

A gene on chromosome 7q32.1 that encodes a subunit of H+-ATPase (also known as V-ATPase, vacuolar ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles, which is required for an array of molecular processes, including protein sorting, zymogen activation, receptor-mediated endocytosis and synaptic vesicle proton gradient generation.