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gyrase

   Also found in: Wikipedia 0.01 sec.
gyrase
[jī′rās]
an enzyme that promotes the unwinding of the closed circular deoxyribonucleic acid helix of bacteria.

gyrase
one of the type II topoisomerases involved in the supercoiling of double-stranded circular DNA molecules.


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Third, isolates were assigned to a principal genetic group on the basis of polymorphisms at codon 463 of the katG gene, which encodes catalase peroxidase, and at codon 95 of the gyrA gene, which encodes the A subunit of DNA gyrase (13).
With detailed methods and protocols, contributors address computational strategies, a number of assay methods (for DNA gyrase, topoisomerase IV, bacterial RNA polymerase, bacterial ribosome biogenesis and inhibitors targeting specific translational steps), high-throughput peptide deformylase inhibitor screening, penicillin-binding protein assay methods, methods for assessing the structure and function of cationic antimicrobial peptides, and bacterial efflux pump inhibitors.
 
 
 
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