guanidine

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Related to Guanidino: guanidinium

guan·i·dine

(gwahn'i-dēn, -din),
A strongly basic compound, usually found (in some plants and lower animals) as the hydrochloride; a constituent of creatine and arginine.

guanidine

/gua·ni·dine/ (gwah´nĭ-dēn) the compound NHdbondC(NH2)2, a strong base found in the urine as a result of protein metabolism and used in the laboratory as a protein denaturant. The hydrochloride salt is used in the treatment of myasthenia gravis.

guanidine

(gwä′nĭ-dēn′)
n.
A strongly alkaline crystalline compound, NHC(NH2)2, formed by the oxidation of guanine and found in the urine as a normal product of protein metabolism. It is commonly used in the organic synthesis of plastics, resins, and explosives.

guanidine

the amidine of amino carbamic acid. The hydrochloride preparation is used to increase acetylcholine release in the treatment of myasthenia gravis and botulism.
References in periodicals archive ?
The first pathway to be discovered for the endogenous production of NO was through the five-electron oxidation of the guanidino nitrogen group of L-arginine (a semiessential amino acid) by a group of enzymes called nitric oxide synthase (NOS) localized to the vascular endothelium.
The uremic toxins, including urea nitrogen, guanidino compounds, such as Cr and methylguanidine, and free radicals, affect renal tissue directly or secondarily, leading to a deterioration of renal function, and producing a vicious cycle that results in renal failure.
That the GAA/(Cr+Crn) ratio was within reference values suggests that the increases in urinary GAA and Cr+Crn could arise from the competition between the two guanidino compounds for the kidney transporter (1).
Post-column derivatization of guanidino compounds in high-performance liquid chromatography using ninhydrin.
Guanidino compounds in serum, urine, liver, kidney, and brain of man and some ureotelic animals.
The diacetyl-a-naphthol method, however, exhibits positive interference from various guanidino compounds and amino acids in erythrocytes (e.
Triethylenetetraminehexaacetic acid (TTHA), potassium ferrocyanide, sodium azide, glutathione (reduced and oxidized forms), ascorbate, and various amino acids and guanidino compounds including creatine were obtained from Sigma.
Various substances, including guanidino compounds and amino acids with chemical structures related to that of creatine and reducing agents, were investigated as to their possible interference with creatine measurement by the present method.
15]N at the guanidino position of L-arginine ends up in nitrite and nitrate.