2013 BPF/BPS Cytotoxicity, genotoxicity, mutagenicity Grignard
In 2008-2009, member Christopher Grignard
was a doctoral student when Yvonne Johnson was brought into a University of Alberta classroom as a guest speaker.
Substitution of the fluorine atoms bonded to the boron center in 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (F-BODIPY) compounds with ethynyl or aryl linkages can be achieved through either Grignard
or lithium organometallic reagents.
Among the topics are solid-phase reactions of polymer-bound arenesulfonates with aryl Grignard
reagents, resin-to-resin transfer reactions through Sonogashira coupling, polyaniline-immobilized palladium for Suzuki-Miyuaura coupling reactions in water, solid-phase reactions of resin-supported boronic acids, and the palladium-catalyzed solid-phase synthesis of allelic amines.
Among these reactions are an electrophilic aromatic substitution, a Williamson ether synthesis, a Grignard
coupling reaction and a Hell-Volhard-Zelinski reaction.
This represents an improvement on the well-established Grignard
method for diaklylations of esters using metallic magnesium and alkyl halides.
Poly(silyleneethynylenephenyleneethynylene)s (PHSEPE, PMSEPE, and PVSEPE) were synthesized by Grignard
method from dichlorosilane and diethynylbenzene with the same molar ratios of 2:3.
Barbier then suggested to Grignard
that he pursue this line of research for a doctoral dissertation .
Hyde picked up Professor Kipping's work on silicones and soon he was preparing lab size quantities of silicone polymers using the Grignard
route, which Kipping pioneered.
The bespoke French race car, chasis number 11006, was delivered new to Georges Grignard
who campaigned it for two years - even winning the 1950 Grand Prix de Paris - and then, after buying another Talbot-Lago, sold it to Roger Laurent, Jacques Swaters and Charles de Tornaco - three amateur Belgian drivers who dreamed of an all-Belgian racing team.
The modified thiophene monomer is polymerized by a Grignard
metathesis reagent to form a polythiophene living intermediate, which reacts with a second thiophene monomer to form an AB block copolymer.
, commander of Belgium's anti-terrorism police unit, says: "The intermingling of terrorist networks with the criminal milieu is becoming more and more important.