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grepafloxacin

   Also found in: Wikipedia 0.02 sec.
grepafloxacin
Raxar® A broad-spectrum quinolone for acute bacterial exacerbation of chronic bronchitis caused by S pneumoniae, H influenzae, Moraxella catarrhalis; community-acquired pneumonia, Mycoplasma pneumoniae; uncomplicated gonorrhea caused by N gonorrhoeae; nongonococcal cervicitis and urethritis due to Chlamydia trachomatis. See Fluoroquinolone.


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Serious adverse drug effects in patients led to the withdrawal or restriction of four quinolones in the past decade (temafloxacin, grepafloxacin, trovafloxacin, and sparfloxacin).
Tatsuo Higuchi; Phone +81-3-3292-0021) and GlaxoSmithKline plc (GSK) have resolved their longstanding dispute relating to the then Glaxo Wellcome's voluntary withdrawal from the market in October 1999 of grepafloxacin (generic name; trade names - RAXAR and VAXAR) by way of compensation payment by GSK to Otsuka.
Comparative bactericidal activities of ciprofloxacin, clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Streptococcus pneumoniae in a dynamic in vitro model.
 
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