transposition of the great vessels

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trans·po·si·tion of the great ves·sels

congenital malformation in which the aorta arises from the morphologic right ventricle and the pulmonary artery from the morphologic left ventricle resulting in two separate and parallel circulations. The condition is lethal unless some communication exists between the systemic and pulmonic circulation after birth; otherwise, unoxygenated venous blood inappropriately enters the systemic circulation, and oxygenated pulmonary venous blood is inappropriately directed to the pulmonary circulation. The life-sustaining communication may be an intraatrial passage or a patent ductus arteriosus.

transposition of the great vessels

a congenital cardiac anomaly in which the pulmonary artery arises from the left ventricle and the aorta from the right ventricle and there is no communication between the systemic and pulmonary circulations. Life is impossible with this anomaly unless there are associated cardiac defects, such as a septal defect or a patent ductus arteriosus, that enable the mixing of oxygenated and unoxygenated blood. The severity of the condition depends on the type and size of the associated defect. The primary symptoms are cyanosis and hypoxia, especially in infants with small septal defects, although cardiomegaly is usually evident a few weeks after birth. Signs of congestive heart failure develop rapidly, especially in infants with large ventricular septal defects. Definitive diagnosis is based on cardiac catheterization. Surgical correction of the defect is postponed, if possible, until after 6 months of age, when the infant can better tolerate the procedure. Immediate palliative surgical procedures such as the Rashkind procedure may be performed to decrease pulmonary vascular resistance and prevent congestive heart failure. See also blue baby.
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Transposition of the great vessels

trans·po·si·tion of the great ves·sels

(trans'pŏ-zish'ŭn grāt ves'ĕlz)
Congenital malformation in which the aorta arises from the morphologic right ventricle and the pulmonary artery from the morphologic left ventricle, resulting in two separate and parallel circulations. The condition is lethal unless some communication exists between the systemic and pulmonic circulation after birth; the life-sustaining communication may be an abnormal interatrial passage or a patent ductus arteriosus.

transposition of the great vessels

One of the types of congenital heart disease. In this condition, the AORTA, the main supply artery of the body, is wrongly connected to the right ventricle, which normally pumps blood returning from the body to the lungs. The pulmonary artery is connected to the left ventricle. As a result, the lungs are effectively bypassed and the blood supplied to the body is insufficiently oxygenated. There is blueness of the skin (cyanosis), breathlessness and failure to thrive. Heart surgery is usually necessary.