gray baby syndrome
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gray baby syndrome.

See gray syndrome.

Gray Syndrome

A condition that may occur when chloramphenicol levels exceed 70 µg/mL; premature infants are most susceptible, given their limited capacity to glucuronidate and excrete chloramphenicol, the functional deficiency in glucuronyl transferase activity corrects itself within the first 3–4 wks of life; high levels of chloramphenicol inhibit mitochondrial electron transport, disrupting energy metabolism; in children < 1 month of age, doses should be 25 mg/kg
Lab Clourimetry, GLC, HPLC, microbiologic, radioenzymatic methods

gray syndrome [gra]

a potentially fatal condition seen in neonates, particularly premature infants, due to a reaction to chloramphenicol, characterized by an ashen gray cyanosis, listlessness, weakness, and hypotension. Called also gray baby syndrome.

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gray baby syndrome (redirected from Gray sydnrome)

gray baby syndrome
(redirected from Gray sydnrome)