Graves disease


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Related to Graves disease: hypothyroidism, Hashimoto's disease

Graves dis·ease

(grāvz), [MIM*275000] Avoid the incorrect forms Grave and Grave's.
1. toxic goiter characterized by diffuse hyperplasia of the thyroid gland, a form of hyperthyroidism; exophthalmos is a common, but not invariable, concomitant finding;
2. thyroid dysfunction and all or any of its clinical associations;
3. an organ-specific autoimmune disease of the thyroid gland.

Graves dis·ease

(grāvz di-zēz')
1. Toxic goiter characterized by diffuse hyperplasia of the thyroid gland, a form of hyperthyroidism; exophthalmos is a common, but not invariable, concomitant finding.
2. Thyroid dysfunction and all or any of its clinical associations.
3. An organ-specific autoimmune disease of the thyroid gland.
See: thyrotoxicosis, Hashimoto disease, goiter, myxedema
Synonym(s): Parry disease.

Graves,

Robert James, Irish physician, 1796-1853.
Graves disease - thyroid dysfunction and all or any of its clinical associations. Synonym(s): Basedow disease; Marsh disease; ophthalmic hyperthyroidism; Parry disease
Graves ophthalmopathy - exophthalmos associated with thyroid disease. Synonym(s): endocrine ophthalmopathy; Graves orbitopathy
Graves orbitopathy - Synonym(s): Graves ophthalmopathy

Marsh,

Sir Henry, Irish physician, 1790-1860.
Marsh disease - Synonym(s): Graves disease

disease

pathogenic entity characterized by an identifiable aetiological agent, group of signs and symptoms and/or consistent anatomical alterations; see syndrome

Graves dis·ease

(grāvz di-zēz') [MIM*275000]
1. Toxic goiter characterized by diffuse hyperplasia of the thyroid gland, a form of hyperthyroidism.
2. Thyroid dysfunction and all or any of its clinical associations.
3. Organ-specific autoimmune disease of thyroid gland.
Synonym(s): Basedow disease.
References in periodicals archive ?
Key Words: anticardiolipin antibodies, Graves disease, hyperthyroidism, livedo reticularis, thyroid
Treatment regimen for Graves disease and the development of spontaneous hypothyroidism Spontaneous Regimen Number Dosage (a) hypothyroidism Methimazole 17 10 mg daily 2 (11.
The patient's serum thyrotropin immunoglobulin level was slightly elevated at 220 mg/dl (normal, <130 mg/dl), confirming Graves disease.
Such occurrences should not be a problem, however, because patients with Graves disease with hyperthyroidism should have TSH concentrations below the reference interval (<0.
Graves disease, celiac disease and idiopathic hypoparathyroidism are all thought be autoimmune in pathogenesis.
Thyroid autoantibody profiles in ophthalmic dominant and thyroid dominant Graves disease differ and suggest ophthalmopathy is a multiantigenic disease.
Thymic hyperplasia presenting as anterior mediastinal mass in 2 patients with Graves disease.
Quantification of thyrotropin-receptor antibodies is important in the diagnosis and management of patients with Graves disease (1).
Graves disease is an autoimmune disorder characterized by hyperthyroidism attributable to thyroid-stimulating hormone (TSH)3 receptor autoantibodies with thyroid-stimulating activity (1-3).
Diagnosis of Graves disease can be difficult because healthy pregnant women may exhibit tachycardia, palpitations, mild heat intolerance, emotional lability, diaphoresis, and warm, moist skin.
These include the TheraTest product line which is used to confirm diagnosis of SLE, rheumatoid arthritis and other connective tissue diseases, and a quantitative thyrotropin receptor antibodies (TRAb) assay which is used for diagnosis of Graves disease.
Hyperthyroidism in Graves disease is attributable to autoantibodies to the thyroid-stimulating hormone receptor (TSHR), and measurement of these TSHR autoantibodies (TRAbs) can be useful in disease diagnosis and management (1-4).