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granisetron

   Also found in: Wikipedia 0.06 sec.
granisetron /gran·is·e·tron/ (gră-nis´ĕ-tron) an antiemetic used in conjunction with cancer chemotherapy or radiotherapy, administered as the hydrochloride salt.
granisetron
[granis′etron]
an antiemetic used in conjunction with cancer chemotherapy or radiotherapy, administered orally or intravenously as the hydrochloride salt.

granisetron
a 5-HT3-antagonist with potent antiemetic activity.

granisetron
Kytril® Oncology A 5-HT3–serotonin receptor antagonist antiemetic used for Pts receiving chemotherapy–eg, cisplatin, cyclophosphamide Adverse effects Headache–35%, constipation–30%, asthenia, somnolence, diarrhea


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Granisetron is commonly used in reducing side effects of antitumor therapy.
APF530, which contains the 5HT3 antagonist anti-nausea drug granisetron formulated with the Company's proprietary Biochronomer[TM] bioerodible drug delivery system, is being developed for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) in patients undergoing either moderately or highly emetogenic chemotherapy.
APF530, which contains the 5HT3 antagonist anti-nausea drug granisetron formulated with the Company's proprietary Biochronomer[TM] bioerodible drug delivery system, is being developed for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) in patients undergoing either moderately or highly emetogenic chemotherapy for cancer.
 
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