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granisetron

   Also found in: Wikipedia 0.03 sec.
granisetron /gran·is·e·tron/ (gră-nis´ĕ-tron) an antiemetic used in conjunction with cancer chemotherapy or radiotherapy, administered as the hydrochloride salt.
granisetron
[granis′etron]
an antiemetic used in conjunction with cancer chemotherapy or radiotherapy, administered orally or intravenously as the hydrochloride salt.

granisetron [gră-nis´ĕ-tron]
an antiemetic used in conjunction with cancer chemotherapy or radiotherapy; administered orally or intravenously as the hydrochloride salt.

granisetron
a 5-HT3-antagonist with potent antiemetic activity.

granisetron
Kytril® Oncology A 5-HT3–serotonin receptor antagonist antiemetic used for Pts receiving chemotherapy–eg, cisplatin, cyclophosphamide Adverse effects Headache–35%, constipation–30%, asthenia, somnolence, diarrhea


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Food and Drug Administration (FDA) of its Abbreviated New Drug Applications (ANDAs) for Granisetron Hydrochloride Injection, 1 mg/mL, 1 mL single dose, and 1mg/mL, 4mL multiple dose vials, the generic equivalent of Hoffmann-LaRoche's Kytril Injection.
The recommended premedication for CDDP was dexamethasone 10 mg and granisetron 1 mg or ondansetron 32 mg administered IV, and adequate prehydration.
In patients at risk of postoperative nausea and/or vomiting it may be useful to administer dexamethasone and dehydrobenzperidol (Droperidol) or a 5HT-antagonist (ondansetron, granisetron, tropisetron, dolasetron) at the start of surgery.
 
 
 
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