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Graft versus host disease |
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Graft versus host disease A life-threatening complication of bone marrow transplants in which the donated marrow causes an immune reaction against the recipient's body. Mentioned in: Bone Marrow Transplantation How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The side effects are part of graft versus host disease (GvHD), an undesirable immune response mounted against an individual receiving a bone marrow stem cell transplant. Because this unique cell population does not include immune system T cells from donors, it opens up the possibility of carrying out a stem cell transplant without the risk of inducing Graft Versus Host Disease. The company has two ongoing Phase II clinical trials with PROCHYMAL to treat graft versus host disease, a life threatening disease affecting patients who have received bone marrow transplants. |
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