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Graft versus host disease

   Also found in: Acronyms, Wikipedia, Hutchinson 0.02 sec.
Graft versus host disease
A life-threatening complication of bone marrow transplants in which the donated marrow causes an immune reaction against the recipient's body.

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The side effects are part of graft versus host disease (GvHD), an undesirable immune response mounted against an individual receiving a bone marrow stem cell transplant.
Because this unique cell population does not include immune system T cells from donors, it opens up the possibility of carrying out a stem cell transplant without the risk of inducing Graft Versus Host Disease.
The company has two ongoing Phase II clinical trials with PROCHYMAL to treat graft versus host disease, a life threatening disease affecting patients who have received bone marrow transplants.
 
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