Grönblad-Strandberg syndrome

Grönblad-Strandberg syndrome

[grōn′blad strand′bərg]

Etymology: Ester E. Grönblad, Swedish ophthalmologist, 1898-1942; James V. Strandberg, Swedish dermatologist, 1883-1942

an autosomal-recessive disorder of connective tissue characterized by premature aging and breakdown of the skin, gray or brown streaks on the retina, and hemorrhagic arterial degeneration, including retinal bleeding that causes vision loss. Angina pectoris and hypertension are common. Weak pulse, episodic cramplike pains in the calves, and fatigue with exertion may affect the extremities. The prognosis depends on vessel involvement, but life expectancy is shortened. Treatment is symptomatic. Also called pseudoxanthoma elasticum.