References in periodicals archive ?
PellePharm, a BridgeBio company, is committed to targeting rare genetic dermatological conditions, including Gorlin Syndrome and basal cell carcinomas.
Conservative treatment of recurrent ovarian fibromas in a young patient affected by Gorlin syndrome.
Gorlin syndrome (also known as Gorlin-Goltz syndrome) is a condition characterised by multiple odontogenic keratocysts, basal cell carcinoma, congenital skeletal abnormalities, cleft lip and/or palate, and eye anomalies.
If it wasn't for the genetics department we would never have known about gorlin syndrome, " added the mum-of-three.
US-based biopharmaceutical company PellePharm has presented topline data from its phase 2 trial evaluating the safety and efficacy of topical patidegib in patients with Gorlin Syndrome, a rare genetic disease that causes patients to develop multiple basal cell carcinomas, the company said.
Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9.
In Gorlin syndrome, various low-frequency neoplasms have been recorded.
20 October 2010 - Scotland-based company Ambicare Health Ltd announced today that Dr Ernest Allan will be presenting a new independent research on the use of Ambulight PDT to treat skin cancer in patients with Gorlin Syndrome at the Gorlin Syndrome Group Annual Patient Conference on 23 October in Birmingham.
Importantly, these data demonstrate proof-of-concept for the therapeutic utility of vismodegib for BCC in Gorlin syndrome patients, for whom there is no approved pharmacological standard of care intervention.
Curis believes that these data are significant because they demonstrate proof-of-concept for the therapeutic utility of vismodegib for BCC in Gorlin syndrome patients, for whom there is no approved pharmacological standard of care intervention.
NASDAQ: CRIS), a drug development company seeking to develop next generation targeted small molecule drug candidates for cancer treatment, today announced the presentation of interim Phase II clinical data on Hedgehog pathway inhibitor vismodegib in patients with basal cell nevus syndrome (BCNS), which is also commonly referred to as Gorlin syndrome.