Gorlin's syndrome

Gor·lin's syndrome

(gôr′lĭnz)
References in periodicals archive ?
OTCQB:HPPI), a clinical stage biopharmaceutical company that discovers, develops and plans to commercialize innovative therapeutics for patients with cancer, announced today that initial patients have received base-line screening and the first of those patients has begun dosing in HPPI's Phase II(b) clinical trial examining SUBA(TM) Itraconazole Capsules as a potential therapy for basal cell carcinoma (BCC) in patients with basal cell carcinoma nevus syndrome (BCCNS), also known as Gorlin's Syndrome.
I have facial disfigurement because of Gorlin's syndrome.
A 10-year-old girl with Gorlin's syndrome presented for evaluation of bilateral tonsillar lesions.
Gorlin's syndrome (basal cell nevus syndrome) is an autosomal-dominant disorder with complete penetrance and variable expression.
The hedgehog pathway caught the attention of cancer researchers when studies revealed that people with Gorlin's syndrome, a hereditary condition that leaves a person highly susceptible to medulloblastoma, often lack a protein that acts as a brake on the pathway, says Berman.
The IND covers HPPI's clinical development plan for a patented formulation of itraconazole (known as SUBA-Itraconazole) with improved bioavailability to study the treatment of basal cell carcinoma (BCC) in patients with basal cell carcinoma nevus syndrome (BCCNS), also known as Gorlin's syndrome, an orphan disease with no approved pharmaceutical therapy.
NBCCS is also known as Gorlin-Goltz syndrome, Gorlin's syndrome, and basal cell nevus syndrome.