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Goodpasture syndrome

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Goodpasture syndrome
Goodpasture's disease, lung purpura-glomerulonephritis, pneumorenal syndrome An idiopathic autoimmune disorder most common in young white ♂, characterized by alveolar hemorrhage, lung infiltrates, renal failure due to rapidly-progressive glomerulonephritis Clinical Hemoptysis, SOB, URIs, fatigue, chest pain, iron-deficiency anemia, acute renal failure Prognosis Poor; average survival, 15 wks Treatment Plasmapheresis, immunotherapy


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Siebels M, Andrassy K, Ritz E: Provocation of pulmonary haemorrhage in Goodpasture syndrome by chlorine gas.
 
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