good

(redirected from Good Works)
Also found in: Dictionary, Thesaurus, Legal, Financial, Idioms, Encyclopedia, Wikipedia.

good

Drug slang
noun A regional term for PCP or heroin.
 
Medspeak
adjective Referring to well-being, benefit.

leukemia

Hematology An uncommon–incidence, US 3.5/105/yr—malignant clonal expansion of myeloid or lymphoid cells characterized by an ↑ in circulating WBCs; leukemias may be an incidental finding when evaluating an unrelated clinical problem, or when the expansion compromises BM production of one or more cell lines causing anemia, thrombocytopenia, granulocytopenia; leukemias are divided by chronology–acute or chronic, by cell lineage–lymphoid, myeloid/myelocytic, monocytic or megakaryocytic and divided by stage of maturation or cell size Clinical BM infiltration by leukemia, resulting in anemia, thrombocytopenia, granulocytopenia, immune paralysis, ↓ B cells and CD4–helper T cells, ↑ CD8–suppressor T cells, infiltration and leukostasis, cranial nerve palsies, meningitis, lymphadenopathy, hepatosplenomegaly, testicular and cutaneous involvement, metabolic derangements–eg, ↑ Ca2+, K+, LD, ammonia, weight loss, less commonly, autoimmune hemolytic anemia, pallor and arthralgia Diagnosis Hx, physical exam, peripheral smear Management Chemotherapy, RT, BMT. See Accelerated leukemia, Acute leukemia, Acute lymphocytic leukemia, Acute myelocytic leukemia, Acute promyelocytic leukemia, Adult T-cell leukemia-lymphoma, Aleukemic leukemia, Biphenotypic leukemia, Central nervous system leukemia, Chemotherapy-induced leukemia, Chronic leukemia, Chronic lymphocytic leukemia, Chronic myelocytic leukemia, Chronic myelomonocytic leukemia, Congenital leukemia, Erythroleukemia, FAB classification, Hairy cell leukemia, Hand mirror cell leukemia, Herald state of leukemia, Mast cell leukemia, Megakaryoblastic leukemia, Multilineage leukemia, Plasma cell leukemia, Preleukemia, Prolymphocytic leukemia, Promyelocytic leukemia, Smoldering myeloid leukemia.
Leukemia Acute v. Chronic
Acute leukemia More common in children, 80% are ALL, often before age 10, peak at ages 3–7 in whites, ♂:♀ ratio, 1.3:1 Cell types Early pre-B cell 67%; pre-B cell 18%; B cell 1%; T cell 14%; 50-85% are cALLA positive–common acute lymphocytic leukemia antigen, CD10; 5% have Philadelphia chromosome Clinical ALL is more abrupt than AML, with petechial hemorrhage, bone and abdominal pain, headache and vomiting due to ↑ intracranial pressure, lymphadenopathy, splenomegaly, hepatomegaly Lab 70% have low-grade lymphocytosis–< 20 x 109 when diagnosed Evaluation Acute leukemia immunophenotypic profile Specimen EDTA–lavender top tube and sodium heparin–green top tube, peripheral blood smears Method of analysis Flow cytometry, immunofluorecesence Markers measured CD1, -2, -3, -4, -5, -7, -8, -10, -19. -20, -21, -33, -34, -56, megakaryocytic markers, HLA D/DR, kappa, lambda, TdT Management Protocols vary according to standard- or high-risk clinical features, and may include BMT
Chronic leukemia More common in adults/older children, often myelocytic; CML is Philadelphia chromosome positive; may occur < age 5 with myelomonocytosis, anemia, thrombocytopenia, lymphadenopathy; WBC count < 50 x 109, ≠ HbF, ≠ muraminidase; adult CML comprises 20% of all leukemias Clinical Gradual onset of fatigability, anorexia, splenomegaly; lymphadenopathy is uncommon Lab > 25 x 109/L leukemic cells in blood–often an absolute lymphocytosis of > 15 x 1010/L, < 10% blasts in BM, myeloid:erythroid ratio is 10-30:1, 90% of cases have low-to-absent leukocyte alkaline phosphatase and rarely also, ≠ vitamin B12 and B12-binding capacity Evaluation Chronic leukemia immunophenotype profile Specimen EDTA–lavender top tube and sodium heparin–green top tube, peripheral blood smears Method of analysis Flow cytometry, immunofluorescence Markers measured CD3, -5, -19, -20, -21, kappa, lambda Management see Chemotherapy, Induction Prognosis see Remission.
Leukemia–prognostic features
Acute lymphocytic leukemia
Good Age 2-10, CD10 positivity, hyperdiploid karyotype
Poor Age < 2; >10, B-cell phenotype, especially L2 phenotype by FAB classification, presence of chromosome translocations, CNS involvement, mediastinal masses, high initial WBC count
Acute myelocytic leukemia
Good Younger, presence of Auer rods, rapid therapeutic response
Poor Older, prior malignancy or therapy, multiple chromosome defects  
References in periodicals archive ?
In addition to Clarkson, Hill and Catchings, the 2016 Allstate NABC and WBCA Good Works Team[sup.
From the nominees submitted by sports information directors across the nation on behalf of their schools, a special voting panel consisting of former Allstate AFCA Good Works TeamA members and prominent college football media members will select the 2014 Good Works Team.
For those of you with your own belief system that may suggest that accumulated good works go towards your score for a place in the after life, here's a thought.
I challenged the professor, pointing out that in Luther's key treatise on "The Freedom of the Christian" (1520), he doesn't say one should not do good works, but that one should do good works gratuitously; that is, we should do all good works for our fellow humans to express our gratitude to God for God's free choice of us regardless of our sins, rather than doings good works to win "Brownie points" from God.
They should take the time to ensure that the recognition of good work is sent up the chain of command as well as down to the line officers.
This is the 17th consecutive season the Allstate/AFCA Good Works Teams( )have been selected, and the first that Allstate has partnered with the AFCA to present the awards.
An indulgence removes some punishment for sin in response to certain prayers, almsgiving, or good works.
There's something beyond just the idea of doing good works that compels well-off doctors to thrust themselves into such desperate situations, something that ``ER'' episode (and the debut episode of the quickly canceled CBS series ``Presidio Med'') hinted at, and that crucial insight into their subjects is what's missing here.
They might not only have become part of a general discourse from which they might have learned things that would have benefited their designs, they might also eventually have through good works found work that would have been able to provide more substantive and interesting responses to 11 September.
Allstate Insurance Company and the American Football Coaches Association (AFCA) have announced the list of 71 student-athlete nominees for the 17th annual Allstate AFCA Good Works Team[R].
15, 2015 /PRNewswire/ -- Allstate Insurance Company and the American Football Coaches Association (AFCA) announced today the roster for the 2015 Allstate AFCA Good Works Team[sup.
Because I would also do a "touch and go" in Ephesians, I rarely quoted verse 10 which says, "For we are God's workmanship, created in Christ Jesus to do good works, which God prepared in advance for us to do.