No immortalized human gonadotrope cells
exist that are not transformed, as occurs in cancer.
Both SMAD2 and SMAD3 mediate activin-stimulated expression of the follicle-stimulating hormone [beta] subunit in mouse gonadotrope cells
," Molecular Endocrinology 18(3): 606-623.
The gonadotrope cells
of the pituitary produce luteinizing hormone (LH) and FSH under the control of hypothalamic gonadotropin-releasing hormone (GnRH).
4 shows that plant extracts diminish the immuno-reactive LH rate released by gonadotrope cells
In 3 patients rapid, sustained decreases in luteinizing hormone/follicle stimulating hormone (LH/FSH) levels, indicative of EP-100 activity on gonadotrope cells
in the anterior pituitary were noted.
Mono-(2-ethylhexyl) phthalate (MEHP) regulates glucocorticoid metabolism through 11[beta]-hydroxysteroid dehydrogenase 2 in murine gonadotrope cells
," Biochemical and Biophysical Research Communication 389(2): 305-309.