(redirected from Gonadotrope cell)


1. a type of basophil in the adenohypophysis whose granules secrete follicle-stimulating hormone and luteinizing hormone.
2. a gonadotropic substance.


/go·nado·trope/ (go-nad´ah-trōp) gonadotroph.

gonadotrope, gonadotrop, gonadotroph

a basophilic cell of the anterior pituitary specialized to secrete follicle-stimulating hormone or luteinizing hormone.
References in periodicals archive ?
In 3 patients rapid, sustained decreases in luteinizing hormone/follicle stimulating hormone (LH/FSH) levels, indicative of EP-100 activity on gonadotrope cells in the anterior pituitary were noted.
Mono-(2-ethylhexyl) phthalate (MEHP) regulates glucocorticoid metabolism through 11[beta]-hydroxysteroid dehydrogenase 2 in murine gonadotrope cells," Biochemical and Biophysical Research Communication 389(2): 305-309.
The gonadotrope cells of the pituitary produce luteinizing hormone (LH) and FSH under the control of hypothalamic gonadotropin-releasing hormone (GnRH).
4 shows that plant extracts diminish the immuno-reactive LH rate released by gonadotrope cells.
Both SMAD2 and SMAD3 mediate activin-stimulated expression of the follicle-stimulating hormone [beta] subunit in mouse gonadotrope cells," Molecular Endocrinology 18(3): 606-623.
No immortalized human gonadotrope cells exist that are not transformed, as occurs in cancer.