gonadotropin-releasing hormone analogue

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gonadotropin-releasing hormone analogue

A polypeptide analogue of gonadotropin-releasing hormone–GnRH; some are more potent than GnRH in stimulating gonadotropin release Examples Leuprolide, histrelin, administered in a pulsatile fashion to restore lost GnRH, normalize pituitary-gonadal function, as in congenital GnRH deficiencies–eg, hypogonadotropic hypogonadism with Kallmann syndrome or without anosmia, or in acquired GnRH deficiency secondary to RT of the CNS, pituitary tumors, or panhypopituitarism. See Gonadotropin-releasing hormone.
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Similar improvements in pain were also observed by our group with both an intrauterine device medicated with levonorgestrel and with a GnRH analog (Hum.
Building contracts are continuous supply of GnRH analog and antiestrogens in the desired size, for a period of two years according to the current needs of the client.
In addition to Striant(TM) SR, Ardana has a rich development portfolio including the Gonadotrophin Releasing Hormone (GnRH)-antagonist, Teverelix LA, in Phase II trials in patients with prostate cancer and benign prostate hyperplasia, Chronodyne(R) (terbutaline) which is in Phase I/II trials for endometriosis-related infertility (being developed in collaboration with Columbia Laboratories and a reformulation of the GnRH analog 'Leuprorelin' which is in Phase II trials for prostate cancer.
Diamond therefore recommends prior treatment of late-stage endometriosis with GnRH analog and possibly surgery when there is hope of reducing endometriomas, improving the environment for ART, and reducing toxicity associated with extensive endometriosis.
The SABERMate product delivers controlled release deslorelin, a GnRH analog, which stimulates leuteinizing hormone (LH) release for advancing and timing the ovulation process.
Lupron, the GnRH analog given to some patients with endometriosis, also may attenuate the bladder symptoms by changing the hormonal environment.
Side effects of GnRH analog treatment have included a reaction, such as redness, swelling, or itching, at the site of injection.
Lupron[R] is among the most common GnRH analogs used as part of this process.
SUPPRELIN LA is contraindicated in patients with hypersensitivity to GnRH or GnRH analogs.
The drugs, known as GnRH analogs, block release of the hormone, thereby poreventing the production of estrogen.
The take-home message is that men on GnRH analogs are at greatly increased risk for osteoporosis and fractures, Dr.
Both GnRH analogs prevent premature hormonal rises (i.