glycoprotein

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glycoprotein

 [gli″ko-pro´tēn]
any of a class of conjugated proteins consisting of a compound of protein with a carbohydrate group.
α1-acid glycoprotein an acute phase protein found in blood plasma, an indicator of tissue necrosis and inflammation. Called also orosomucoid.
P-glycoprotein a cell-surface protein occurring normally in the colon, small intestine, adrenal glands, kidney, and liver, and also expressed by tumor cells. It is a modulator of multidrug resistance, mediating the transport of antineoplastic agents out of tumor cells.
variable surface glycoprotein any of several glycoproteins that form the antigenic protein coating of Trypanosoma brucei. The organisms contain numerous genes encoding hundreds of such glycoproteins and, by expressing individual ones successively, evade the immune system of the host.

gly·co·pro·tein

(glī'kō-prō'tēn),
1. One of a group of proteins containing covalently linked carbohydrates, among which the most important are the mucins, mucoid, and amyloid.
See also: mucoprotein.
2. Proteins containing small amounts of carbohydrate, in contrast to mucoids or mucoproteins, usually measured as hexosamine; such conjugated proteins are found in many places, notably γ-globulins, α1-globulins, α2-globulins, and transferrin, and are contained in mucus and mucins.
See also: mucoprotein.

glycoprotein

/gly·co·pro·tein/ (-pro´tēn) a conjugated protein covalently linked to one or more carbohydrate groups; technically those with less than 4 per cent carbohydrate but often expanded to include the mucoproteins and proteoglycans.

glycoprotein

(glī′kō-prō′tēn′, -tē-ĭn)
n.
Any of a group of conjugated proteins having a carbohydrate as the nonprotein component.

glycoprotein

[glī′kōprō′tēn]
Etymology: Gk, glykys, sweet, proteios, first rank
any of the large group of conjugated proteins in which the nonprotein substance is a carbohydrate. These include the mucins, the mucoids, and the chondroproteins.

gly·co·pro·tein

(glī'kō-prō'tēn)
1. One of a group of protein-carbohydrate compounds (conjugated proteins), among which the most important are the mucins, mucoid, and amyloid.
2. Sometimes restricted to proteins containing small amounts of carbohydrate, in contrast to mucoids or mucoproteins.
See also: mucoprotein

glycoprotein

Any member of a class of proteins linked to carbohydrate units. They are called conjugated proteins and are of comparatively small molecular weight. Some, such as follicle stimulating hormone, luteinizing hormone and chorionic gonadotropin, lose their function if the sugar part is removed; others can continue to function even if deglycosylated. Some glycoproteins are cell adhesion molecules.

glycoprotein

any PROTEIN that contains sugars as part of the molecule.

glycoprotein

One of a group of conjugated proteins formed by a protein and a carbohydrate, the most important being the mucins (as found in the lens capsule, vitreous humour) and mucoids (as found in bones, cartilage, tendons).

gly·co·pro·tein

(glī'kō-prō'tēn)
One of a group of proteins containing covalently linked carbohydrates, among which the most important are the mucins, mucoid, and amyloid.

glycoprotein

any of a class of conjugated proteins consisting of a compound of protein with a carbohydrate group.

glycoprotein deficiency
an inherited disorder in dogs in which there is defective phagocytic function. Affected dogs have a marked, persistent neutrophilia and are susceptible to infections.
alpha-2HS glycoprotein
important in bone resorption.
References in periodicals archive ?
With the increased sensitivity and resolution power of up-to-date analytical techniques, it is still of crucial importance to distinguish properly, natural heterogeneity from heterogeneity arising from contaminating glycoproteins.
This research is part of an effort to implicate glycoproteins in several processes, like protein stabilization and potential allergenic cross-reactivity in wine.
Hyperglycemia in experimental diabetic rats leads to a decreased utilization of glucose by insulin dependent pathways, thereby enhancing the formation of glycoproteins (Youngren et al.
Palmisano and his colleagues believe grape variety and the vinification process influence the amount of glycoproteins in a finished wine.
Typing schemes based on other genes, like the one coding for the glycoprotein gN, have been refined over recent years (7) and can also be used to type Indian strains.
1) The glycoprotein G and non-glycoprotein G ELISA tests were both found to have sensitivities >90%, but the non-glycoprotein G ELISA tests had specificities under 90%.
For example, by learning more about how defensins bind to glycoproteins, researchers one day may be able to devise new drugs that prevent viruses from entering cells.
Since the particular lineup of glycoproteins in a person's saliva stays the same throughout a lifetime, Denny says that testing a child's sugar-chain combination would give a dentist a sense of whether a young patient is at a high or low risk of developing cavities.
For instance, people with type B blood have galactose as part of the glycoproteins in their pellicle and saliva.
GlycoFi is the leader in the area of glycosylation engineering in living systems, and its patented, scaleable technology uniquely allows its partners to create specific human glycosylation variants of any therapeutic glycoprotein.
Our phylogenetic data were based on analysis of the HMPV F protein, one of two viral glycoproteins considered the major antigenic determinant in RSV (11).