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glycoproteinosis

   Also found in: Wikipedia 0.02 sec.
glycoproteinosis
intracytoplasmic accumulations of a complex of glycoprotein and acid mucopolysaccharide in the central nervous system (PAS positive Lafora bodies), associated with seizures in familial progressive myoclonic epilepsy (Lafora's disease) in humans, and also reported in some breeds of dogs, particularly longhaired Dachshunds. Affected dogs have two copies of a mutation in the canine Eph26 gene.


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