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glycogen phosphorylase

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.06 sec.
glycogen phosphorylase /gly·co·gen phos·phor·y·lase/ (gli´ko-jen fos-for´i-las) see phosphorylase.
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Discovered by (OSI) Prosidion, OSI's diabetes and obesity team, PSN357 is a glycogen phosphorylase inhibitor (GPI), which is designed to rapidly lower blood glucose levels by preventing glycogen breakdown to glucose in the liver.
OSI INITIATES PHASE I CLINICAL TRIAL OF PSN357 by Worldwide Biotech
Nasdaq: OSIP) announced today that it has initiated a Phase IIa clinical trial for its glycogen phosphorylase inhibitor, PSN357, which the company is developing for type 2 diabetes.
OSI Pharmaceuticals Announces Initiation of Phase IIa Trial for Its ... by Business Wire
Other product candidates include a glycogen phosphorylase inhibitor currently in a Phase I clinical trial and a glucokinase activator scheduled to enter a Phase I clinical trial in 2006.
OSI Pharmaceuticals Grants License Under Dipeptidyl Peptidase IV ... by Business Wire
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