In addition, pathway analysis revealed that EGCG was involved in the regulation of the lipid and glucose metabolism, including insulin signaling pathway, Type II diabetes mellitus, glycerophospholipid
metabolism, and adipocytokine signaling pathway.
Evidence of phospholipase activity coincides with results reported by Cafarchia et al (15) and Pini and Faggi (16), who illustrate this enzyme can be involved in pathogenesis, since it acts by hydrolyzing glycerophospholipid
For this glycerophospholipid
, the OR between extreme tertiles was 0.
Effects of salinity on the fatty acid composition of total lipid and individual glycerophospholipid
classes of Atlantic salmon (Salmo salar) and turbot (Scopthalmus maximus) cells in culture.
Acyltransferases of de novo glycerophospholipid
Kainic Acid-mediated Neural Cell Death in Brain: Interplay among Glycerophospholipid
, Sphingolipid-, and Cholesterol-derived Lipid Mediators
By means of UPLC/MS technology, we found in a previous study that there are significant changes between the phospholipid levels of AMI patients before I/R treatment compared to healthy controls – specifically, glycerophospholipid
is significantly down-regulated and most sphingomyelin are up-regulated.
The derivations of those biomarkers can be regulated by administration of XKS, which suggested that the intervention effect of XKS against AS may involve in regulating the lipid perturbation including fatty acid [beta]-oxidation pathway, sphingolipid metabolism, glycerophospholipid
metabolism and bile acid biosynthesis.
Briefly, the choline glycerophospholipid
fraction obtained from bovine heart muscle was hydrolyzed with 0.
TAHIRA FAROOQUI has published extensively on drug receptor interactions, biogenic amines in vertebrate and invertebrate nervous systems, glycerophospholipid
and sphingolipid metabolism, and molecular mechanisms in the brain, as well as on the neuromodulatory role of octopamine in the reinforcement pathway involved in olfactory learning and memory.
Pathway analysis determined that five pathways corresponded to the dysregulated transcripts [Figure 5] and that the most enriched network was the glycerophospholipid
metabolism network, which is composed of two targeted genes.
Platelet-activating factor (PAF), a potent glycerophospholipid
mediator, is involved in a number of dose-dependent physiological functions such as platelet and neutrophil aggregation, inducement of changes in vascular permeability, anaphylaxis and hypotension (Blank et al.