glutamate receptor

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glutamate receptor

Any of a family of heteromeric protein complexes that are the primary excitatory neurotransmitter receptors in the brain, which are activated by various neurophysiologic stimuli. Glutamate receptors are comprised of multiple subunits, each with transmembrane regions, and form a ligand-gated ion channel. They are classified based on their activation by different pharmacologic agonists.
References in periodicals archive ?
Objective: Glutamate receptors are amongst the most important signalling molecules in the brain.
So, by blocking glutamate receptors, memantine protects healthy cells in the Alzheimer's brain.
Metabotropic glutamate receptors are Class C GPCRs, which respond to the neurotransmitter glutamate.
Research has shown that people are sensitive to MSG and that all organs of the body contain glutamate receptors that MSG can damage.
Glu binds to glutamate receptors (GluRs) leading to the activation of multiple signaling pathways.
Group 1 of these metabotropic glutamate receptors (which modulate the NMDA receptors) are thought be the neurological basis for autism and Fragile X (Chen, 2012).
In embryonic neuronal cultures, DHA supplementation uniquely promoted neurite growth, synapsin puncta formation and synaptic protein expression, particularly synapsins and glutamate receptors.
of the Johns Hopkins University School of Medicine, focuses on a family of proteins called group 1 metabotropic glutamate receptors (mGluRs) that lie on the surfaces of nerve cells.
Among the topics are ionotropic glutamate receptors in the basal ganglia, striatal acetylcholine-dopamine crosstalk and the dorsal-ventral divide, the electrophysiology of the corticostriatal network in vivo, and impaired dopamine-glutamate receptor interactions in some neurological disorders.
Yan and colleagues examined whether repeated stress had a negative influence on glutamate receptors in juvenile rats.
In an effort to improve therapeutic options for patients with schizophrenia, several agents that affect glutamate receptors are being actively studied in randomized, controlled trials.

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