Los genes de interes evaluados para este estudio fueron: Aminomethyltransferase, Glycine dehydrogenase, Glycine hydroxymethyltransferase, [DELTA]-1-pyrroline-5-carboxylate synthase, Ornithine aminotransferase, Arginase, Alanine transaminase, Alanine-glyoxylate transaminase, Glutamate decarboxylase
, Glutamate decarboxylase
1-2, Spermidine synthase, Aldehyde dehydrogenase, ATP-grasp domain-containing protein, Cysteine sulfinic acid decarboxylase1-2, Taurine transporter, HSP beta 1, Sodium- and chloride-dependent glycine transporter (Meng et al.
Producing alkaline GABA and cadaverine, both glutamate decarboxylase
and lysine decarboxylase enzymes have strategic role in neutralizing acidic condition.
Lab analysis of metagenomic DNA sequencing data allowed us to demonstrate that microbial glutamate decarboxylase
encoding gene is very abundant in intestinal microbiota as compared to other body sites," Pokusaeva said.
The main inhibitory mediator in the brain, gamma amino butyric Acid (GABA), is formed from glutamate (excitatory) by the enzyme glutamate decarboxylase
Rapid determination of glutamate decarboxylase
activity from lactic acid bacteria by spectrometric method and its applications.
(GAD) is the unique enzyme to catalyze the conversion of L-glutamate or its salts to GABA through the single-step a-decarboxylation [14,15].
The glutamate decarboxylase
gene and associated metabolites (GABA and glutamic acid) are up-regulated in response to infection in both types of rice, and the glutathione transferase gene and its metabolite (oxidized glutathione) are differentially regulated between the wild-type and the transgenic strains.
Cell origin was confirmed by the presence of mRNA transcripts for: calcium/calm odulin-dependent protein kinase-II (CamK-II) for excitatory pyramidal cells, glutamate decarboxylase
(GAD65) for inhibitory interneurons and glial fibrillary acidic protein (GFAP) for astrocytic cells (see Figure).
GABA is synthesized in a reaction catalyzed by the calmodulin modulated enzyme glutamate decarboxylase
(GAD) that is activated, in part, by stress-induced increases in [Ca.
Sex steroid regulation of glutamate decarboxylase
mRNA expression in goldfish brain is sexually dimorphic.
Two islet autoantibody specificities definitely represent major subfractions of ICAs: antibodies to the 65-kDa isoform of glutamic acid decarboxylase (GAD65-abs) (7, 8) the [gamma]-aminobutyric acid-synthesizing isoform of glutamate decarboxylase
in human islets (9), and antibodies to islet antigen-2 (IA2-abs) (10), a protein tyrosine phosphatase expressed in islet cells that has been described as a membrane protein composed of 979 amino acids (11).
When the mice reached about 4 weeks of age, both terms observed that glutamate decarboxylase
(GAD) began activating T-cells.