FOLH1

(redirected from Glutamate carboxypeptidase II)
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FOLH1

A gene on chromosome 11p11.2 that encodes folate hydrolase 1, which has both folate hydrolase (FH) and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. It acts as an FH in the intestine and is required for the uptake of folate; in the brain, it modulates excitatory neurotransmission by hydrolysing the neuropeptide N-aceylaspartylglutamate (NAAG), releasing glutamate. It is highly expressed in the prostate.
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Abstract No: 9617 induced Nausea and Vomiting Location: S Hall in Patients Receiving High- A1 dose Melphalan Prior to Stem Cell Transplant Poster 46B GCP II Inhibitor Glutamate Carboxypeptidase II May 31, 2008 Abstract No: 9558 Inhibition in Rat Models of 2:00-6:00 p.
Location: S406 (Vista Room) GCP II Glutamate Carboxypeptidase II Inhibition in May 31, 2008 Inhibitor Rat Models of Chemotherapy-induced Peripheral Neurotoxicity 2:00-6:00 Abstract No: p.
Recent Development of Diagnostic and Therapeutic Agents Targeting Glutamate Carboxypeptidase II (GCPII) (Youngjoo Byun, Ronnie C.

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