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glucuronide
(redirected from Glucuronides)

    Also found in: Wikipedia 0.03 sec.
glucuronide /glu·cu·ron·ide/ (gloo-ku´ron-īd) any glycosidic compound of glucuronic acid; they are common soluble conjugates formed as a step in the metabolism and excretion of many toxins and drugs, such as phenols and alcohols.
glu·cu·ro·nide (gl-kyr-nd)
n.
Any of various derivatives of glucuronic acid that often combine with toxic organic compounds and are excreted.
glucuronide
any glycosidic conjugate of glucuronic acid; glucuronides, which are generally inactive, constitute the major proportion of the metabolites of many phenols, alcohols and carboxylic acids.


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In therapeutic doses, adults metabolize APAP predominantly in the liver, rapidly forming nontoxic glucuronides and sulfates that are excreted in urine (1,11) (Fig.
Acetaminophen overdose in pregnancy by Herrera, Jorge L. / Southern Medical Journal
05; Figure 3), but glucuronides were < LOD, as determined by [beta]-glucuronidase treatment.
Expression of xenobiotic metabolizing enzymes in different lung ... by Borlak, Jurgen / Environmental Health Perspectives
However, most is reconjugated into glucuronides or sulfates, the primary circulating forms of genistein, which are thought to have either low or no biological activity.
The science of soy: what do we really know? by Barrett, Julia R. / Environmental Health Perspectives
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