glucuronide

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glucuronide

 [gloo-ku´ron-īd]
any glycosidic compound of glucuronic acid; glucuronides, which are generally inactive, constitute the major proportion of the metabolites of many phenols, alcohols, and carboxylic acids.

glu·cu·ro·nide

(glū-kū'rōn-īd),
A glycoside of glucuronic acid; many foreign chemicals, as well as catabolic products of normal body constituents (for example, steroid hormones), are commonly excreted in the urine as d-glucuronides, the conjugation taking place in the liver.
Synonym(s): glucuronoside

glucuronide

/glu·cu·ron·ide/ (gloo-ku´ron-īd) any glycosidic compound of glucuronic acid; they are common soluble conjugates formed as a step in the metabolism and excretion of many toxins and drugs, such as phenols and alcohols.

glu·cu·ro·nide

(glū-kyūr'ō-nīd)
A glycoside of glucuronic acid; many foreign chemicals, as well as catabolic products of normal body constituents (e.g., steroid hormones), are commonly excreted in the urine as d-glucuronides, the conjugation taking place in the liver.

glucuronide

any glycosidic conjugate of glucuronic acid; glucuronides, which are generally inactive, constitute the major proportion of the metabolites of many phenols, alcohols and carboxylic acids.
References in periodicals archive ?
Improved detection of opioid use in chronic pain patients through monitoring of opioid glucuronides in urine.
This enabled identification of un-metabolised urinary flavonolignans and urinary phase II metabolites, such as glucuronides, sulphate-glucuronides and diglucuronides.
Qualifier ions Isomers (m/z) (m/z) Silychristin 481 125 Silydianin 481 125 SilybinAand B 481 125 Isosilybin A and B 481 125 Silymarin 657 481, 125 16 glucuronides Silymarin sulphate 737 657, 561, 481, 7 glucuronides 125 Silymarin 833 657, 481, 125 8 diglucuronide
The results obtained from the above study were that the compounds were metabolized to glucuronides and sulfates after intravenous administration.
Moreover, flavonoid glucuronides appear to serve as plasma transport metabolites to target cells rather than solely as excretion products.
4] in the liver leads to the formation of sulfates and glucuronides, which enter the bile and pass into the intestine.
In Sprague-Dawley rats, after oral administration of NP, containing 95% of branched side-chain NP isomers, considerable amounts of aromatic ring hydroxylated glucuronides were detected in serum and liver based on MS fragmentation properties (Doerge et al.
CHAPTER 7 ENZYMATIC SYNTHESIS OF GLYCOSIDES AND GLUCURONIDES
Direct quantification of cannabinoids and cannabinoid glucuronides in whole blood by liquid chromatography-tandem mass spectrometry.
Similarly, MRM chromatograms of liver, lungs and pancreas indicated the presence of glucuronides, sulfates and monohydroxylated metabolites of puerarin (Figs.
It is worth noting that the signal of carboxylic acid C6' carbon was not observed, as is frequently the case for glucuronides.
The total bilirubin test measures bilirubin in many forms including those conjugated to glucuronides and those bound to proteins.