, acetylation, and sulfation reactions
Similarly, 2-hydroxyflutamide is metabolized via phase II glucuronidation
and thus is not a noteworthy substrate for the assay's phase I metabolic system (Tevell et al.
6,8) Piperine reduces intestinal glucuronidation
via uridine 5'-diphosphoglucuronosyltransferase inhibition, and the small or moderate effects on lithium levels seem to be the result of diuretic activities.
The 3 primary pathways of elimination and metabolism are glucuronidation
, mitochondrial dependent [beta]-oxidation, and the minor pathway of [OMEGA]-oxidation.
Hepatic enzymes, including both the P450 system and the glucuronidation
pathways, are immature at birth.
Oral testosterone administration detected by testosterone glucuronidation
measured in blood spots dried on filter paper.
When frozen, the skin lost its glucuronidation
These compounds undergo glucuronidation
or sulfation before being excreted by the kidneys.
The in vitro WEL glucuronidation
activities of human liver microsomes, human kidney microsomes, human intestine microsomes, and 12 recombinant human uridine diphosphate-glucuronosyltransferase (UGT) isoforms were screened.
Phase II conjugation reactions include glucuronidation
, glutathione transferases, S-methylation, N-methylation, acetylation, sulfotransferases, thioltransferases, and glycination (amino acid conjugation).
It is well known that SHBG reduces cellular uptake of Te; however we have demonstrated that SHBG may also maintain stable levels of biofunctional Te and physiologically relevant intracellular Te levels by reducing Te glucuronidation
Bioavailability of anthocyanins was extensively studied due to the different mechanisms of the uptake and metabolism (deconjugation, glucuronidation
, sulfation, and deglucuronidation) in various cell lines.