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glucuronidation

   Also found in: Wikipedia 0.01 sec.
glucuronidation (glōō·k·rō·n·dāˑ·shn),
n a phase II detoxification pathway occurring in the liver in which glucuronic acid is conjugated with toxins. Effectively detoxifies the majority of commonly prescribed drugs.


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Further, the EFSA argues that rapid metabolism will result in negligible exposure during the perinatal period because of BPA glucuronidation in pregnant women or sulfation in newborns.
Detoxification mechanisms include methylation, acetylation, sulfation, glucuronidation, oxidation, and others.
One example of the importance of glucuronidation can be seen in the risk factors for breast cancer.
 
 
 
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