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Related to Glucoraphanin: Sulforaphane


An isothiocyanate phytochemical present—after conversion from glucoraphanin by myroinase—in cruciferous vegetables (e.g., Brussels sprouts, broccoli, cabbage), which has anticarcinogenic, antimicrobial and antidiabetic activity in experimental systems. 
It stimulates the production of phase-2 enzymes that play a role in detoxifying carcinogens; in rats, sulphoraphane reduces the incidence of mammary tumours induced by dimethylbenzanthracene (DMBA).


Sulforaphane glucosinolate, sulphoraphane Oncology An isothiocyanate phytochemical or 'nutriceutical' in cruciferous vegetables–eg, broccoli, which may prevent CA. See Cruciferous vegetables, Nutriceutical.


, sulphoraphane (sŭl-fŏr′ă-fān″) [″ + Gr. phainein, to show],


A sulfur-containing compound found in vegetables of the mustard family (Cruciferae). Like other isothiocyanates, it has been shown to prevent cancer in animals.
References in periodicals archive ?
Broccoli contains the highest amount of uber detox antioxidant, glucoraphanin, shown to increase the elimination of carcinogens in the body by 61 percent[1].
Not all foods contain the same amount of glucoraphanin.
Glucoraphanin works by breaking fat down in the body, preventing it from clogging the arteries.
The new broccoli, called Beneforte, contains two to three times more glucoraphanin than standard broccoli.
Farnham says this discovery makes it possible to classify the anticancer potential of different broccoli varieties according to how their glucoraphanin spurs detoxifying enzyme activity in mammalian cells.
Talalay's team found that the key protective compound in broccoli (a chemical called glucoraphanin, which the body turns into sulforaphane) was 20 times more concentrated in young, three-day-old broccoli sprouts than it is in more mature broccoli plants.
These studies leave no doubt that sulforaphane (derived from biogenesis of glucoraphanin in broccoli) does indeed induce phase 2 enzymes which inhibit carcinogenesis.
Glucoraphanin is the precursor to sulforaphane, a potent natural inducer of Phase 2 detoxification enzymes.
Glucoraphanin occurs naturally in broccoli and is thought to help explain the link between consuming broccoli and lower rates of heart disease and some forms of cancer.
2) Glucoraphanin and other phytonutrients play a vital role in cancer prevention, immune system function, and the maintenance of healthy, youthful skin.
Beneforte[R] Broccoli (Launching)Beneforte[R] naturally contains two to three times the phytonutrient glucoraphanin compared with other leading broccoli varieties produced under similar growing conditions, boosting the body's antioxidant enzyme levels at least two times more than other broccoli.
Broccoli contains other anticancer agents as well, such as glucoraphanin.