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gluconeogenesis |
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gluconeogenesis /glu·co·neo·gen·e·sis/ (gloo?ko-ne?o-jen´e-sis) the synthesis of glucose from molecules that are not carbohydrates, such as amino and fatty acids.
gluconeogenesis (gloo´kōnē´ōjen´ n the formation of glycogen or glucose from noncarbohydrate sources (e.g., the glycogenic amino acids, glycerol, lactate, and pyruvate) by pathways mainly involving the citric acid cycle and glycolysis. gluconeogenesis the synthesis of glucose from noncarbohydrate sources, such as amino acids, propionate and glycerol. It occurs primarily in the liver and kidneys whenever the supply of carbohydrates is insufficient to meet the body's metabolic demands or in the rumen by the action of bacteria in well-fed ruminants. Gluconeogenesis is stimulated by cortisol and other glucocorticoids and by glucagon. Formerly called glyconeogenesis. |
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