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glucocerebrosidase

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glucocerebrosidase /glu·co·cer·e·bro·si·dase/ (-ser″ĕ-bro-si´dās) glucosylceramidase.
glucocerebrosidase
Glucosylceramidase An enzyme that catalyzes cleavage of glucose from glucocerebrosides to form acylsphingosine, a cerabmide; its absence is linked to Gaucher's disease


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Food and Drug Administration (FDA) for prGCD, the company's proprietary plant-cell expressed recombinant form of glucocerebrosidase (GCD) for the treatment of Gaucher disease.
Gaucher disease, the most commonly diagnosed lysosomal storage disorder, is caused by inherited genetic mutations in the GBA gene, which result in deficient activity of the enzyme acid beta-glucosidase, also known as glucocerebrosidase (GCase).
[3,4] Clinical features of splenomegaly and an abnormal glucocerebrosidase level are diagnostic.
 
 
 
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