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glucagon-like peptide 1
(redirected from Glucagon-like peptide-1)

   Also found in: Wikipedia 0.06 sec.
glucagon-like peptide 1 (GLP-1),
an appetite suppressing substance found in the brain and intestine. In the brain, GLP-1 acts as a satiety signal. In the intestine it slows emptying of the stomach and stimulates the release of insulin from the pancreas.


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Ehlers will present two abstracts: "Subcutaneous Infusion of GLP-1 for 7 Days Improves Glycemic Control Over a Broad Dose Range in Patients with Type 2 Diabetes" and "Subcutaneous Recombinant Glucagon-like Peptide-1 (rGLP-1) Reduces Food Intake in Obese Subjects".
Liraglutide, a long-acting derivative of the natural hormone glucagon-like peptide-1 (GLP-1), is in Phase III trials.
The development of inhibitors of DPIV (an enzyme catalyzing the breakdown of the natural hormone glucagon-like peptide-1 (GLP-1)) has become a very competitive area in the type 2 diabetes field.
 
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