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glucagon-like peptide 1

   Also found in: Acronyms, Wikipedia 0.04 sec.
glucagon-like peptide 1 (GLP-1),
an appetite suppressing substance found in the brain and intestine. In the brain, GLP-1 acts as a satiety signal. In the intestine it slows emptying of the stomach and stimulates the release of insulin from the pancreas.


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Abstract: Exenatide (synthetic exendin-4) is the analog of glucagon-like peptide 1 (GLP-1), the major physiologic incretin.
Glucagon-like peptide 1 revs up and refurbishes insulin-making cells of the pancreas and might spawn the growth of new cells (164: 104).
Improved glycaemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analogue liraglutide (NN2211): a 12-week, double-blind, randomized, controlled trial.
 
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