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imatinib
(redirected from Glivec)

    Also found in: Wikipedia 0.01 sec.
imatinib /im·at·i·nib/ (ĭ-mă´tĭ-nib″) an antineoplastic used as the mesylate salt in the treatment of chronic myeloid leukemia, inhibiting an abnormal enzyme form constitutively produced in the disease.
imatinib
[imă′tĭnib′]
an inhibitor acting specifically on an abnormal enzyme form that is created by the Philadelphia chromosome abnormality and present in chronic myeloid leukemia. It is administered orally as the mesylate salt in the treatment of chronic myeloid leukemia during blast crisis, accelerated phase, or chronic phase after failure of interferon-alpha therapy.
imatinib [ĭ-mă´tĭ-nib″]
an inhibitor acting specifically on an abnormal enzyme form that is created by the Philadelphia chromosome abnormality and present in chronic myeloid leukemia. It is used in the treatment of chronic myeloid leukemia during blast crisis, accelerated phase, or chronic phase after failure of interferon-α therapy, administered orally as the mesylate salt.
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This resulted in a new drug that was more effective than its parent and produced few of the side effects associated with Glivec.
IRISH SCIENTISTS MAKE CANCER BREAKTHROUGH by The Mirror (London, England)
Novartis also announced on Wednesday that its Glivec cancer treatment has been granted "priority review status" by the United States Food and Drug Administration (FDA) for post-surgery use to treat stomach tumours.
British experts green light Novartis' sight-saving drug by AFP / AFP Global Edition
In 2004, executives at Novartis Oncology discovered that the company's breakthrough leukemia therapy, Glivec, was threatened by a new product projected to gobble up 20 to 30 percent of market share.
Leading high-performance teams: horizontal, high-performance teams ... by Guttman, Howard M. / Chief Executive (U.S.)
 
 
 
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