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thiazolidinedione
(redirected from Glitazone)

    Also found in: Wikipedia 0.01 sec.
thi·a·zo·li·dine·di·one (th-zl-dnd-n, -d-n)
n. Abbr. TZD
A class of drugs used to treat type 2 diabetes mellitus by decreasing insulin resistance.
thiazolidinedione
Glitazone, TZD Endocrinology A class of oral antidiabetic agents that inhibit tyrosine kinase, ↓ insulin resistance and correct hyperglycemia, hyperinsulinemia, hypertriglyceridemia Adverse effects Hepatic dysfunction. See Troglitazone, Tyrosine kinase inhibitor.


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For example, data on the use of the glitazones (eg, troglitazone, rosiglitazone, pioglitazone) to treat HIV-associated lipodystrophy have been conflicting and somewhat disappointing.
Thinking outside of the (pill) box: alternative approaches to ... by Newcomb-Fernandez, Jennifer / Research Initiative/Treatment Action!
The only currently approved anti-diabetic agents that are known to act as insulin sensitizers are the glitazone class of drugs, which collectively represent 48% of the annual sales in the $12 billion per year global oral anti-diabetic market.
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Revenue growth forecasts have been driven by the sales of two of the largest drug classes, namely glitazones (monotherapy/combinations) and insulin, which continue to deliver high growth of 15% and 20% respectively.
The United States Accounted for 50% of the World's ... by Business Wire
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