NLGN3

(redirected from Gliotactin homolog)

NLGN3

A gene on chromosome Xq13.1 that encodes neuroligin 3, a neuronal cell surface protein involved in cell–cell interactions, which forms intercellular junctions by binding to beta-neurexins. It may play role in forming or maintaining synaptic junctions, as well as glia–glia or glia–neuron interactions in the developing peripheral nervous system.
 
Molecular pathology
Defects of NLGN3 have been linked to an increased susceptibility to Asperger syndrome (X-linked type 1) and to autism (X-linked type 1).