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glial cell line-derived neurotrophic factor

   Also found in: Wikipedia 0.01 sec.
glial cell line-derived neurotrophic factor (GDNF)
[glī′əl]
a nerve growth drug that has been used in laboratory animals to reverse the progression of symptoms of Parkinson's disease and other brain diseases. GDNF is believed to act as a biologic shield, protecting nerve cells from damage that normally would destroy them.


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Mandel's research group has concentrated on using an adeno-associated virus to engineer brain cells in animal models with genes that can protect dopamine-producing cells, which then do the vital work of producing glial cell line-derived neurotrophic factor (GDNF).
Common drug can function as 'off switch' for Parkinson therapy by Asian News International
Alterations in expression of the neurotrophic factors glial cell line-derived neurotrophic factor, ciliary neurotrophic factor and brain-derived neurotrophic factor, in the target-deprived olfactory neuroepithelium.
Effect of Ninjin-yoei-to (Rensheng-Yangrong-Tang) on olfactory ... by Yamasaki, Aigo; Sugahara, Kazuma; Takemoto, Tsuyoshi; Ikeda, Takuo; Yamashita, Hiroshi / Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
These molecules include neurotrophic factors such as nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and glial cell line-derived neurotrophic factor [20,67-69].
Potential of olfactory ensheathing cells for cell-based therapy in ... by Radtke, Christine; Sasaki, Masanori; Lankford, Karen L.; Vogt, Peter M.; Kocsis, Jeffery D. / Journal of Rehabilitation Research & Development
 
 
 
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