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glatiramer |
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glatiramer /gla·tir·a·mer/ (glah-tir´ah-mer) an immunomodulator used as the acetate ester to reduce relapses in multiple sclerosis. glatiramer, a multiple sclerosis drug. indication It is used to reduce the frequency of relapses in patients with relapsing-remitting multiple sclerosis. contraindications Known hypersensitivity to this drug or to mannitol prohibits its use. adverse effects Adverse effects include migraine, palpitations, syncope, tachycardia, vasodilation, nausea, vomiting, diarrhea, anorexia, gastroenteritis, ecchymosis, lymphadenopathy, edema, weight gain, arthralgia, anxiety, hypertonia, tremor, vertigo, speech disorder, agitation, confusion, bronchitis, dyspnea, pruritus, rash, sweating, urticaria, erythema, ear pain, urinary urgency, dysmenorrhea, and vaginal moniliasis. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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This chapter presents a number of different treatment approaches including 2 approved drugs: interferon beta (treatment of choice for patients with active relapsing disease) and glatiramer acetate (alternative to interferon beta). CONFIRM will also include a glatiramer acetate (Copaxone([R])) reference comparator arm. First, we'll learn if combining two drugs with two different mechanisms of action works better than either one alone; next, we'll get data on how an interferon stacks up against glatiramer acetate, and finally, through separate funding from NINDS (National Institute for Neurologic Disease and Stroke) we expect to identify 'biomarkers' for guiding treatment choice," Dr. |
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