thrombasthenia /throm·bas·the·nia/ (throm″bas-the´ne-ah) a platelet abnormality characterized by defective clot retraction and impaired ADP-induced platelet aggregation; clinically manifested by epistaxis, inappropriate bruising, and excessive posttraumatic bleeding.
thrombasthenia
thrombasthenia (throm´basthē´nē
),
thrombasthenia
Glanzmann thrombasthenia thrombasthenia.
throm·bas·the·ni·a (thr m b s-th  n- ) or throm·bo·as·the·ni·a (thrmb -s-)n. An abnormality of blood platelets, as in Glanzmann's thrombasthenia. |
thrombasthenia
[throm′basthē′nē·ə]
Etymology: Gk, thrombos, lump, a + sthenos, not strength
a rare hemorrhagic disease characterized by a defect in platelet-mediated hemostasis caused by an abnormality in the membrane surface of the platelet. The platelets do not aggregate, a clot does not form, and hemorrhage ensues. Transfusion with platelets is effective in controlling the hemorrhage. The condition is an inherited autosomal-recessive trait.
thrombasthenia (throm´basthē´nē
),n a hemorrhagic diathesis associated with qualitative abnormalities of the platelets.
thrombasthenia
a platelet abnormality characterized by defective clot retraction and impaired ADP-induced platelet aggregation. There are mild bleeding tendencies. Inherited as an autosomal recessive disorder in Otterhounds. Called also Glanzmann's disease, Glanzmann-Naegeli syndrome.
thrombasthenia
Glanzmann's disease, see there
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