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thrombasthenia |
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thrombasthenia /throm·bas·the·nia/ (throm″bas-the´ne-ah) a platelet abnormality characterized by defective clot retraction and impaired ADP-induced platelet aggregation; clinically manifested by epistaxis, inappropriate bruising, and excessive posttraumatic bleeding. Glanzmann thrombasthenia thrombasthenia.
thrombasthenia [throm′basthē′nē·ə] Etymology: Gk, thrombos, lump, a + sthenos, not strength a rare hemorrhagic disease characterized by a defect in platelet-mediated hemostasis caused by an abnormality in the membrane surface of the platelet. The platelets do not aggregate, a clot does not form, and hemorrhage ensues. Transfusion with platelets is effective in controlling the hemorrhage. The condition is an inherited autosomal-recessive trait. thrombasthenia (throm´basthē´nē n a hemorrhagic diathesis associated with qualitative abnormalities of the platelets. thrombasthenia a platelet abnormality characterized by defective clot retraction and impaired ADP-induced platelet aggregation. There are mild bleeding tendencies. Inherited as an autosomal recessive disorder in Otterhounds. Called also Glanzmann's disease, Glanzmann-Naegeli syndrome. thrombasthenia Glanzmann's disease, see there How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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