As early as 1970, studies showed that ginkgo extract
exerts therapeutic effects on cardiovascular diseases.
2010; van Beek and Montoro 2009) In fact, extensive clinical research has found that standardized ginkgo extract
may reduce patients' risk of developing a number of mental diseases, including Alzheimer's.
The authors undertook research to investigate the influence of a specific type of ginkgo extract
, EGb761[R] on embryofoetal development in mice during the critical period of organogenesis (6th to 15th day of pregnancy) by oral administration to the dams.
Direct and indirect cholinergic activity has been reported with administration of ginkgo extract
in vitro (Das 2002, Nathan 2000).
In the French GuidAge study, groups of elderly people with memory complaints were randomly assigned 240 milligrams per day of ginkgo extract
, or a placebo, to be taken daily.
They were randomized either to twice-daily doses of placebo or 120 mg of ginkgo extract
And, regarding that higher dose, we see the need for a purer Ginkgo extract
containing terpene lactones at a much higher concentration.
They were randomized to twice-daily doses of either placebo or 120 mg of ginkgo extract
, which entered the market in Germany in 1982, is now used by more than 10 million Europeans annually, is government approved, and is covered by insurance and the German national health care system (17).
To determine effectiveness of ginkgo versus placebo in reducing the incidence of all-cause dementia and AD in elderly individuals with normal cognition and those with mild cognitive impairment (MCI), US Ginkgo Evaluation of Memory Study investigators randomised 3000 volunteers aged 75 years or older to receive twicedaily doses of 120mg ginkgo extract
or matching placebo.
In earlier lab tests, ginkgo extract
showed an ability to protect brain cells from the sort of problems that occur in Alzheimer's patients.
The Ginkgo extract
was given (on average) as two to three coated 40 mg tablets mixed in with the food once a day by the pet owners.