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There is no effective chemoprophylaxis for this disease. Metronidazole, quinacrine, or tinidazole are preferred treatments. See: water, emergency preparation of safe drinking
Cysts or trophozoites can be identified in feces. Three consecutive negative tests are required before the feces are considered to be negative. Duodenal contents also can be examined by aspiration or string test, in which an ordinary string is swallowed and allowed to remain in the duodenum long enough for the protozoa to attach. On removal, it is examined for the presence of cysts or trophozoites. A stool antigen assay test detects Giardia. This involves either immunofluorescence or enzyme-linked immunosorbent assay.