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Giant Cell Reaction

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Giant Cell Reaction
Any reparative tissue reaction with multinucleated epithelioid histiocytes that may be due to exogenous material (e.g., sutures) or endogenous material (e.g., the contents of a ruptured epidermal inclusion cyst, chalazion or fat)

giant cell reaction
Any reparative tissue reaction with multinucleated epithelioid histiocytes, that may be due to exogenous material–eg, sutures, or endogenous material–eg, the contents of a ruptured epidermal inclusion cyst, chalazion, or fat


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Synovial hyperplasia and giant cell reaction in response to intact and fragmented plastic prosthetic joints have been well known for many years.
10) Possible reported complications associated with gastrointestinal teratomas include adenocarcinoma, (6) ulceration, rupture and bleeding, (4,7) foreign body giant cell reaction secondary to keratinous contents, (3,4) regional lymphadenopathy, (3) intestinal obstruction, (2) failure to thrive, (8) and anemia.
These cells surrounded stalks of stroma that contained blood vessels with foamy histiocytes, extensive hemorrhage, ischemic necrosis, and foreign body giant cell reaction to cholesterol (Figures 2 and 3).
 
 
 
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