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Giant Cell Myocarditis

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myocarditis /myo·car·di·tis/ (-kahr-di´tis) inflammation of the muscular walls of the heart.
acute isolated myocarditis  a frequently fatal, idiopathic, acute myocarditis affecting chiefly the interstitial fibrous tissue.
Fiedler's myocarditis  acute isolated myocarditis
giant cell myocarditis  a subtype of acute isolated myocarditis characterized by the presence of multinucleate giant cells and other inflammatory cells, and by ventricular dilatation, mural thrombi, and wide areas of necrosis.
granulomatous myocarditis  giant cell myocarditis, including also granuloma formation.
hypersensitivity myocarditis  that due to allergic reactions caused by hypersensitivity to various agents, particularly sulfonamides, penicillins, and methyldopa.
interstitial myocarditis  that affecting chiefly the interstitial fibrous tissue.

Giant Cell Myocarditis
A severe, idiopathic, possibly autoimmune-related inflammatory heart disease of young, otherwise healthy adults, which may be a virally induced immune reaction to underlying encephalitis, hepatitis, infection, intoxication, nutritional defects, thymoma, thyroiditis, Wegener’s granulomatosis, etc.
Prognosis 70% mortality
Management Heart transplant


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