germ-free animal

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germ-free animal

a laboratory animal raised under sterile conditions, free of exposure to microorganisms. The diet is controlled, preventing exposure to microorganisms that may be in food. The germ-free animals have lymphoid tissue that is not fully developed and may have a deficiency of serum immunoglobulin.
References in periodicals archive ?
1965) History of germfree animal research at Lobund Laboratory, Biology Department, University of Notre Dame, 1928-1965.
Use of the germfree animal technic in the study of experimental dental caries.
His group then transplanted gut flora from a lean or obese mouse into a germfree animal and fed all treated rodents the same amounts.
Similarly, gastric emptying and intestinal transit are more delayed in germfree animals (41).