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genotype |
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genotype /ge·no·type/ (-tīp) 1. the entire genetic constitution of an individual; also, the alleles present at one or more specific loci. 2. the type species of a genus.genotyp´ic
genotype [jē′nōtīp′] Etymology: Gk, genos, birth, typos, mark 1 the complete genetic constitution of an organism or group, as determined by the specific combination and location of the genes on the chromosomes. 2 the alleles situated at one or more sites on homologous chromosomes. A pair of alleles is usually designated by letters or symbols, such as AA when the alleles are identical and Aa when they are different. 3 a group or class of organisms having the same genetic makeup; the type species of a genus. Compare phenotype. genotypic, adj. genotype (jēˑ·nō·tīp), n an organism's genetic makeup.
genotype (jē´nōtīp), n the aggregate of ordered genes received by offspring from both parents; e.g., a person with blood group AB is of genotype AB.
genotype 1. the entire genetic constitution of an individual; also, the alleles present at one or more specific loci. 2. the type species of a genus. genotype frequency
the proportion of the population which have the same genetic constitution. genotype The complete genetic constitution of an individual at a particular location (locus) in the genome. At many locations (loci) throughout the genome, the chromosomal DNA sequence differs subtly between individuals. Each of the various DNA sequences at one locus is called an allele: for instance, if there are three sequence variants present, then there are three alleles. Offspring inherit one homologous chromosome from each parent. Thus, a genotype comprises two alleles: the allele inherited from the father (carried on the paternal chromosome) and the allele inherited from the mother (carried on the maternal chromosome). See gene; phenotype.
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We found a significant increase in mean titer of homologous DENV-1 neutralizing antibodies and a significant decrease in heterologous antibodies to 1 of 2 genotypes of DENV-2 virus (the American genotype). The primary goals of our analysis were to examine associations of ALAD, VDR, and eNOS genotype with uric acid in lead workers while controlling for other covariates and to evaluate whether ALAD, VDR, and eNOS genotypes modified associations between the lead dose biomarkers (tibia lead, blood lead, DMSA-chelatable lead) and uric acid while controlling for other covariates. The prototype securely stores information on patient genotypes and compares them with drug evidence to indicate an optimal choice and dosage of drugs according to a genotype of each patient. |
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