epistasis

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Related to Genetic interaction: epistasis

epistasis

 [ĕ-pis´tah-sis]
1. suppression of a secretion or excretion, as of blood, menses, or lochia.
2. the interaction between genes at different loci, as a result of which one hereditary character is unexpressed, or is masked by the superimposition of another upon it. See also dominance. adj., adj epistat´ic.

e·pis·ta·sis

(e-pis'tă-sis),
1. The formation of a pellicle or scum on the surface of a liquid, especially as on standing urine.
2. Phenotypic interaction of nonallelic genes.
3. A form of gene interaction whereby one gene masks or interferes with the phenotypic expression of one or more genes at other loci; the gene the express phenotype of which is said to be "epistatic," whereas the phenotype altered or suppressed is then said to be "hypostatic."
Synonym(s): epistasy
[G. scum; epi- + G. stasis, a standing]

epistasis

(ĭ-pĭs′tə-sĭs)
n. pl. epista·ses (-sēz′)
1. An interaction between nonallelic genes in which the genotype at one locus affects the expression of alleles at another locus.
2. A film that forms over the surface of a urine specimen.
3. The suppression of a bodily discharge or secretion.

ep′i·stat′ic (ĕp′ĭ-stăt′ĭk) adj.

epistasis

[epis′təsis]
Etymology: Gk, a standing
1 suppression of a secretion or excretion, as of blood, menses, or lochia.
2 an interaction between genes at different loci in which one gene masks or suppresses the expression of the other. Epistasis, which is nonallelic and therefore different from dominance, may be caused by the presence of homozygous recessive alleles at one gene pair, as occurs in the Bombay phenotype, or by the presence of a dominant allele at one locus that counteracts the expression of a dominant allele at the other locus. Compare dominance. epistatic, adj.

e·pis·ta·sis

(e-pis'tă-sis)
1. The formation of a pellicle or scum on the surface of a liquid, especially on standing urine.
2. Phenotypic interaction of nonallelic genes.
3. A form of gene interaction whereby one gene masks or interferes with the phenotypic expression of one or more genes at other loci; the gene with the expressed phenotype is said to be epistatic, the phenotype altered or suppressed is then said to be hypostatic.
[G. scum; epi- + G. stasis, a standing]
Epistasisclick for a larger image
Fig. 152 Epistasis . The interaction of genes A and B.

epistasis

a form of genetic interaction in which one gene interferes with the expression of another gene, as when, for example, genes A and B code for enzymes active in the same PATHWAY. See Fig. 152 . If both ALLELES of gene A code for a nonfunctional version of enzyme A, then the pathway will shut down, irrespective of which B alleles are present, i.e. gene A is epistatic to gene B. Compare DOMINANT EPISTASIS, RECESSIVE EPISTASIS.

epistasis,

n gene interaction where a gene at a particular locus supercedes or obscures the expression of another gene at a different locus.

e·pis·ta·sis

(e-pis'tă-sis)
Formation of a pellicle or scum on the surface of a liquid, especially as on standing urine.
[G. scum; epi- + G. stasis, a standing]

epistasis

non-allelic masking of one gene by another, e.g. the masking of the black gene by the orange gene in tortoiseshell cats.
References in periodicals archive ?
This actually led to ignoring the potential genetic interaction effects in the genetic analysis, especially without single-locus additive and dominance effects (Carlborg and Haley, 2004).
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The increased attention that PCOS has gained over the past decade has influenced research projects to explore genetic interactions and predispositions, environmental issues, and the effects of new treatments.
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These early genetic studies resulted in the establishment of functional relationships among various factors in regulation of gene expression through analysis of their genetic interactions.
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A companion study is under way to assess genetic interactions with diet on the risk of cardiovascular disease and diabetes.
We are eager to apply genome-wide screening to identify, learn and target the complex genetic interactions in human cancer cells to improve patient care.
In addition, genetic interactions of this QTL with other genes including Ppd-1, Vrn-1, and 1DL QTL will be defined, informing breeders of what alleles can be selected simultaneously for additive or interactive effects on heading date and pleiotropic phenotypes.
The more information we acquire about genetic interactions, the more effective scientists can be in developing bench-to-bedside research," she added.