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epistasis |
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epistasis [epis′təsis] Etymology: Gk, a standing 1 suppression of a secretion or excretion, as of blood, menses, or lochia. 2 an interaction between genes at different loci in which one gene masks or suppresses the expression of the other. Epistasis, which is nonallelic and therefore different from dominance, may be caused by the presence of homozygous recessive alleles at one gene pair, as occurs in the Bombay phenotype, or by the presence of a dominant allele at one locus that counteracts the expression of a dominant allele at the other locus. Compare dominance. epistatic, adj. epistasis, n gene interaction where a gene at a particular locus supercedes or obscures the expression of another gene at a different locus. epistasis non-allelic masking of one gene by another, e.g. the masking of the black gene by the orange gene in tortoiseshell cats. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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These early genetic studies resulted in the establishment of functional relationships among various factors in regulation of gene expression through analysis of their genetic interactions. BIND's data model was the first of its kind to be peer-reviewed prior to database development, and is now a mature standard data format spanning molecular interactions, small molecule chemical reactions, interfaces from three-dimensional structures and genetic interaction networks. Such research could include the evolution of haplotypes, selection for genetic interactions, and the evolution of recombination and methylation patterns. |
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