Genetic disease

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genetic disease

A generic term for any–inherited condition caused by a defective gene–eg, an 'inborn error of metabolism'

Genetic disease

A genetic disease is a disease that is passed from one generation to the next, but does not necessarily appear in each generation. An example of genetic disease is Down's syndrome.
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genetic disease,

n a disease that is caused by a defect or anomaly in the genetic inheritance of the patient.

Patient discussion about Genetic disease

Q. what makes Arthritis a genetic disease?

A. First of all, the term arthritis is a bit inaccurate: Arthritis denotes an inflammation of joints. There are many kinds of arthritis that may result from different causes, and therefore, are different diseases: septic arthritis (inflammation due to infection of joint) has much less genetic background than ankylosing spondylitis (an arthritis of the lower back joints that occurs almost exclusively in people with certain genetic background).

The arthritis with the genetic background are usually the autoimmune ones: Due to genetic determinants, the immune system of some people is programmed to recognize the various parts of the joints (and other organs as well) as foreign (i.e. like bacteria) and thus launches an attack on them. In normal immune system, that doesn't happen.

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Q. Is bipolar disease a hereditary problem? My only son is in his teens that is the age to enjoy life, but he cannot enjoy his life with his friends because we found that he is suffering from a bipolar condition. I feel so sad for him and though my care-free days have gone, I often think about how much fun I had at his age. I too suffered from a bipolar disorder and my mom too. Is bipolar disease a hereditary problem? I want him to help to enjoy his life.

A. I agree with you. No one should suffer because of hereditary problems. This is the same situation here as genes are passed from generation to generation. This information is inconclusive because many who may have had bipolar disorders did not have it checked out. Who is to say, how many people 50 years ago had it but dismissed it as being moody, or ill tempered. Doctors were not aware about this problem years ago. Some time back, someone who showed signs of a mental disorder was straight away shoved into a mental hospital and left to suffer. Besides they are often treated with electric shock therapy eventually getting out of control. Testing is still in progress to find out if genetics play a role but these theories may take several more years before they can have a better understanding.

Q. Is FMS heredetery? My mother was diagnosed with FMS and I would like to know what are the chances I’ll have it too.

A. Hereditary is not the right term. It’s not a genetic disease but The cause of fibromyalgia remains elusive. However, recent studies show that genetic factors can predispose individuals to a genetic susceptibility to fibromyalgia.

More discussions about Genetic disease
References in periodicals archive ?
Genetic testing allows the genetic diagnosis of susceptibilities to inherited or genetic diseases, In addition to studying chromosomes to the level of individual genes, genetic testing in a broader sense includes biochemical tests for the possible presence of genetic diseases, or mutant forms of genes associated with increased risk of developing genetic disorders.
The finding advances our ability to predict how severe any inherited genetic diseases will be in each affected person, a key insight into human disease.
At Genzyme we continue the mission to develop and deliver transformative therapies to all patients affected by rare genetic diseases.
The sequencing of genetic diseases will lead to a change in our medical practices.
4 million with deficiency allele combinations (phenotypes PiSS, PiSZ, and PiZZ) for the two most prevalent deficiency alleles PiS and PiZ; therefore, the new data suggest that AAT deficiency may be one of the most common serious single-locus genetic diseases in the world.
We are highly focused on repurposing both old drugs and shelved assets across many genetic diseases because of the translational acceleration that comes with finding new uses for compounds for which a great deal is already known, and the speed with which we've moved this project forward illustrates these benefits nicely.
Such "repeats" usually repeat themselves fewer than 30 times, but research has identified 18 human genetic diseases associated with expansion of the number of these repeats, sometimes into the thousands.
MPS-VI (also known as Maroteaux-Lamy syndrome) is a progressive, chronically debilitating genetic disease that proceeds from birth and results in early death.
The probability that a child will be afflicted with one of the genetic disease is 3.
Ataxia-telangiectasia (A-T) is a rare genetic disease that attacks children, causing progressive loss of muscle control, immune system problems, and a high rate of cancer.
A group of patients whose genetic disease was already known were investigated in a pilot trial.